The WHO has extensive data from almost countries on more health measures than you could imagine — definitely worth a look one rainy, wintry afternoon.
So I began to think. It links together the sympathetic and parasympathetic nervous system, with the actions of the stress hormones, the adrenal glands, thyroxine, glucagon, insulin etc.
A complex beast of a thing.
Bjorntorp established that chronic psychological stress chronic strain creates a dysfunction of the HPA-axis that can be monitored, most easily, by looking at twenty-four-hour cortisol secretion.
A dysfunctional HPA-axis leads to a flattened and unresponsive burnt-out cortisol release during the day. This does not mean cortisol levels are high, or low, they just flat-line.
He studied various populations e. Sweden and Lithuania, and found that the Lithuanians at the time were far more likely to have a dysfunctional HPA-axis than the Swedes, and their rate of CVD was four times as high as that in Sweden.
A study done only on men at the time. I then started to look at other conditions where the HPA-axis is damaged. Depression, schizophrenia — in fact almost all psychiatric illness — PTSD, survivors of childhood abuse.
In all cases the same pattern emerged. I detoured round spinal cord injury. Most people are probably unaware that spinal cord injury is associated with a very much higher rate of CVD. People who suffer spinal cord injury also have a damaged HPA-axis.
Some more than others. It depends on the level of the damage, and whether or not the autonomic nervous system is damaged. It travels down the spine, but not in the spinal canal].
I then had a look at corticosteroids. These are the drugs used in many diseases as anti-inflammatory agents. Which is why they are called corticosteroids steroids manufactured in the cortex of the adrenal gland.
They are fantastic drugs, and widely used. The more I looked, the more it seemed very clear that the unconscious neuro-hormonal system was the key player in CVD, both heart attacks and strokes.
It also seemed that cortisol was probably the lynch pin. Which is why my favourite graph on CVD comes from Lithuania. I have used it before, and I make no bones about using it again.
The rate of heart disease in Lithuania was gradually falling during the s, until the year At which point the Berlin wall came down, the Soviet Union broke apart and the structure of society was torn apart. It was a very, very, stressful time.
Coronary heart disease (CHD) is responsible for significant morbidity and mortality in elderly patients (i.9%) than white women (%) and higher for black men . Mayo Clinic Health Letter provides reliable, authoritative and accurate health information. Discover why it is one of the leading health publications. ORIGINAL ARTICLE. The Yanomami indians in the INTERSALT study. Jairo de Jesus Mancilha-Carvalho; Nelson Albuquerque de Souza e Silva. Hospital Universitário Clementino Fraga Filho of the Universidade Federal do Rio de Janeiro (FM/UFRJ), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)/MCT and .
What happened to the rate of heart disease in men, under Latvia and Estonia showed the same pattern, as did Russia three years later when Gorbachov was deposed by Yeltsin. In non-Soviet European countries, nothing happened.
Heart disease rates continued their gentle fall.
I had been looking for evidence that abrupt social disruption leads to stress which leads to CVD. During war medical statistics tend to get overlooked, or other causes of sudden death distort the picture.Coronary Artery Disease 10/31/ This paper will serve as a case study for the condition known as coronary artery disease (CAD).
CAD occurs when the coronary arteries become hardened and narrowed; this is due to the buildup of plaque on the inner lining of the arteries.4/4(1). combcodes catcode labels combcodes anesthesia for procedures on arteries of upper arm and elbow; not otherwise anesthesia for procedures on arteries of upper arm and elbow; embolectomy.
A couple weeks ago, I had the pleasure of giving a presentation to a tri-chapter meeting of the Medical Library Association. The topic was why some patients with chronic disease are disaffected and how online social networks have met some of their needs.
September CoQ10 improves cardiac function in MVD-affected dogs in first canine study. In a September article, Thai veterinary cardiologists (Kittipong Tachampa [right], Tuchakorn Lertwanakarn, Panupong Atchariyasakchai, Vichayanee Pumpitakkul, Supapatt Kireewan, Chollada Buranakarl) tested 13 dogs in congestive heart failure (CHF) due to mitral valve disease .
Coronary heart disease refers to a narrowing of the coronary arteries, the blood vessels that supply oxygen and blood to the heart. It is also known as coronary artery disease. It is a major cause. Mayo Clinic Health Letter provides reliable, authoritative and accurate health information. Discover why it is one of the leading health publications.